miRNA description for miR-122-5p
miRNA accession miR-122-5p
Species Homo sapiens
 miR-122-5p identified in exosomes derived from the following tissue/cell type
Hepatoma cells [Exosomes] 29963269   
Hepatoma cells [Exosomes] 29963269   
Plasma [Exosomes] 36455873   
Plasma [Exosomes] 36455873   
Plasma [Extracellular vesicles/Exosomes] 31762962   
Pulmonary artery endothelial cells [Exosomes] 32132543   
Pulmonary artery endothelial cells [Exosomes] 32132543   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Extracellular vesicles] 29887978   
Serum [Exosomes] 27883272   
Serum [Exosomes] 27883272   
 Experiment description of studies that identified miR-122-5p in exosomes
1
Experiment ID753
Identified moleculemiRNA
Identification method PCR
PubMed ID 29963269   
OrganismHomo sapiens
Experiment descriptionMining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury
AuthorsUen Y, Wang JW, Wang C, Jhang Y, Chung JY, Tseng T, Sheu M, Lee S.
Journal name Oncotarget
Publication year2018
SampleHepatoma cells
Sample nameHuh-7
Molecules identified in the studymiRNA
Methods used in the studyPCR
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2
Experiment ID755
Identified moleculemiRNA
Identification method PCR
PubMed ID 29963269   
OrganismHomo sapiens
Experiment descriptionMining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury
AuthorsUen Y, Wang JW, Wang C, Jhang Y, Chung JY, Tseng T, Sheu M, Lee S.
Journal name Oncotarget
Publication year2018
SampleHepatoma cells
Sample nameHep3B
Molecules identified in the studymiRNA
Methods used in the studyPCR
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3
Experiment ID2027
Identified moleculemiRNA
Identification method RT-qPCR
PubMed ID 36455873   
OrganismHomo sapiens
Experiment descriptionSevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF
AuthorsZhao J, Zhang W, Wang S, Li Z, Huang Y, Li L.
Journal name Aging
Publication year2022
SamplePlasma
Sample namePatients with post-operative cognitive dysfunction (POCD)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Small RNA sequencing
RT-qPCR
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4
Experiment ID2028
Identified moleculemiRNA
Identification method RT-qPCR
PubMed ID 36455873   
OrganismHomo sapiens
Experiment descriptionSevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF
AuthorsZhao J, Zhang W, Wang S, Li Z, Huang Y, Li L.
Journal name Aging
Publication year2022
SamplePlasma
Sample namePatients without post-operative cognitive dysfunction (non-POCD)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Small RNA sequencing
RT-qPCR
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5
Experiment ID2317
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameNon-smokers
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
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6
Experiment ID1468
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 32132543   
OrganismHomo sapiens
Experiment descriptionTherapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension
AuthorsSindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B.
Journal name Nat Commun
Publication year2020
SamplePulmonary artery endothelial cells
Sample nameHPAEC
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
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7
Experiment ID1469
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 32132543   
OrganismHomo sapiens
Experiment descriptionTherapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension
AuthorsSindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B.
Journal name Nat Commun
Publication year2020
SamplePulmonary artery endothelial cells
Sample nameHPAEC
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
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8
Experiment ID1032
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (ExoRNeasy)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
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9
Experiment ID1034
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (qEV)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
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10
Experiment ID1035
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Volunteer (Exo-spin)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
11
Experiment ID1036
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (Exo-spin)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
12
Experiment ID1037
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Volunteer (miRCURY)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
13
Experiment ID1038
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 29887978   
OrganismHomo sapiens
Experiment descriptionEvaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.
AuthorsBuschmann D, Kirchner B, Hermann S, Mäe M, Wurmser C, Brandes F, Kotschote S, Bonin M, Steinlein OK, Pfaffl MW, Schelling G, Reithmair M.
Journal name J Extracell Vesicles.
Publication year2018
SampleSerum
Sample nameSerum - Sepsis patient (miRCURY)
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Next generation sequencing
EV-TRACK -
14
Experiment ID1198
Identified moleculemiRNA
Identification method Microarray
PubMed ID 27883272   
OrganismHomo sapiens
Experiment descriptionCirculating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.
AuthorsHubal MJ, Nadler EP, Ferrante SC, Barberio MD, Suh JH, Wang J, Dohm GL, Pories WJ, Mietus-Snyder M, Freishtat RJ.
Journal name Obesity (Silver Spring).
Publication year2017
SampleSerum
Sample nameTwo weeks before bariatric surgery
Molecules identified in the studymiRNA
Metabolites
Methods used in the studyMass spectrometry
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15
Experiment ID1199
Identified moleculemiRNA
Identification method Microarray
PubMed ID 27883272   
OrganismHomo sapiens
Experiment descriptionCirculating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.
AuthorsHubal MJ, Nadler EP, Ferrante SC, Barberio MD, Suh JH, Wang J, Dohm GL, Pories WJ, Mietus-Snyder M, Freishtat RJ.
Journal name Obesity (Silver Spring).
Publication year2017
SampleSerum
Sample nameOne year after bariatric surgery
Molecules identified in the studymiRNA
Metabolites
Methods used in the studyMass spectrometry
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